TropIQ’s technology platform includes facilities for semi-automated cell culture, a vector lab for entomological experiments and liquid dispensing and state-of-the-art signal detection equipment. TropIQ has developed a unique barcoded live insect screening technology for discovery of novel vector control agents (insecticides, repellents, attractants, chemosterilants) and malaria transmission-blocking molecules.
Live insect screens:
High throughput barcoded screen of insecticides in systemic and contact mode.
Screening of transmission blocking compounds and antibodies.
- Standard membrane feeding assay (SMFA)
- High throughput barcoded screen in multiwell format
In vitro high throughput assays for all malaria (Plasmodium falciparum) life cycle stages:
- asexual blood stages
- liver stages
- Supply of malaria life cycle stages and processed material from P. falciparum wild type and transgenic GFP/luciferase parasites
- Supply of monoclonal antibodies against various epitopes of sexual stage antigens (Pfs48/45, Pfs25, Pfs230)